Document Type

Article

Publication Title

Electrocatalytic Cyclopropanation of Active Methylene Compounds

Corresponding Author(s)

Hai-Chao Xu (haichao.xu@xmu.edu.cn)

Abstract

The development of novel strategies to access cyclopropanes has become increasingly important due to the vital role of these three-membered ring structures in synthetic intermediates, natural products, and pharmaceuticals. Herein, we present an electrocatalytic method for the synthesis of cyclopropanes through intermolecular dehydrogenative annulation of active methylene compounds and arylalkenes. This electrochemical process requires no chemical oxidants, allowing for a speedy access to various functionalized cyclopropanes from inexpensive and readily available materials.

Graphical Abstract

Keywords

electrochemistry, cyclopropane, catalyst, alkene, organic electrosynthesis

Online Date

7-11-2023

SI-2313001.pdf (6430 kB)

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.