Authors
Yan Chen, Information Materials and Intelligent Sensing Laboratory of Anhui Province, Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, P.R. China; Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of Education, Anhui University, Hefei, 230601, P.R. China.
Jian Shang, SINOCHEM International Advanced Materials (Hebei) CO., LTD. Technology Branch, Shijiazhuang, 050000, P.R. China.
Siyu Wan, Information Materials and Intelligent Sensing Laboratory of Anhui Province, Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, P.R. China; Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of Education, Anhui University, Hefei, 230601, P.R. China.
Xiaotong Cu, Information Materials and Intelligent Sensing Laboratory of Anhui Province, Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, P.R. China; Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of Education, Anhui University, Hefei, 230601, P.R. China.
Zhonggang Liu, Information Materials and Intelligent Sensing Laboratory of Anhui Province, Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, P.R. China; Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of Education, Anhui University, Hefei, 230601, P.R. China.
Zheng Guo, Information Materials and Intelligent Sensing Laboratory of Anhui Province, Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, P.R. China; Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of Education, Anhui University, Hefei, 230601, P.R. China.
Corresponding Author(s)
Zhonggang Liu(zhgliu@ahu.du.cn);
Zheng Guo(zhguo@ahu.edu.cn)
Abstract
Metal-organic framework (MOF) nanostructures have emerged as a prominent class of materials in the advancement of electrochemical sensors. The rational design of bimetallic MOF-functionalized microelectrode is of importance for improving the electrochemical performance but still in great challenge. In this work, bimetallic FeCo-MOF nanostructures were assembled onto a gold disk ultramicroelectrode (Au UME, 5.2 µm in diameter) via an in-situ electrodeposition method, which enhanced the sensitive detection of epinephrine (EP). The FeCo-MOF, characterized by a nanoflower-like morphology, was uniformly dispersed on the ultra-micro substrate. The FeCo-MOF/Au UME demonstrated excellent electrochemical performance on the detection of EP with a high sensitivity of 36.93 μA μM-1 cm-2 and a low detection limit of 1.28 μM. It can be attributed to the non-linear diffusion of EP onto the ultra-micro working substrate, coupled with synergistical catalytic activity of the bimetallic Fe, Co within MOF structure. Furthermore, FeCo-MOF/Au UME has been successful applied to the analysis of EP in human serum samples, yielding high recovery rates. These results not only contribute to the expansion of the research area of electrochemical sensors but also provide novel insights and directions for the development of high-performance MOF-based electrochemical sensors.
Graphical Abstract
Keywords
FeCo-MOF, Au disk ultramicroelectrode, in-situ electrodeposition, electroanalysis, epinephrine
DOI
10.61558/2993-074X.3516
Recommended Citation
Yan Chen, Jian Shang, Siyu Wan, Xiaotong Cui, Zhonggang Liu, Zheng Guo. In-situ Electrodeposition of FeCo-MOF on Au Ultramicroelectrode for Highly Sensitive Detection of Epinephrine[J]. Journal of Electrochemistry, doi: 10.61558/2993-074X.3516.
