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Abstract

The electrochemical behavior of ascorbic acid(AA),uric acid(UA),L-cystein(L-Cys)and acetaminophen(APAP),i.e.the main interference to the GOD electrode,were studied at the Pt,GC and powder microelectrode. Experimental results indicated that,due to the electrochemical activity of these interference,it is difficult to eliminate their interference effects by manipulation of electrede materials or working potential of the GOD electrode. However,it was found that the limiting curtents at the KB electrode are mainly controlled by mass transfer in liquid phase,so it is only related to the geometer size of the electrode,not its rcal surface area. Therefore,it is possible to enhance significantly the signal/noise ratio of the GOD electrode by using the powder microelectrode technique.

Keywords

Powder microelectrode, GOD electrode, Ascorbic acid, uric acid, L-cystein, Acetaminophen

Publication Date

1996-08-28

Online Available Date

1996-08-28

Revised Date

1996-08-28

Received Date

1996-08-28

References

1ClarkLC,LyonsL.Electrodesystermforcontinuousmonitoringincardiovascularsurgery.Ann.NY.Acad.Sci.,1962,102:29~452BindraDS,ZhangY,WilsonGS.Designandinvitrostudiesofaneedle-typeglucosesensorforsubcutaneousmonitoring.Anal.Chem.,1991,63:16923MoussyF,JakewayS,HarrisonDJetal.Invitroandinvivoperformanceandlifetimeofper-fluorinatedionomer-coatedglucosesensorsafterhigh-temperaturecuring.Anal.Chem.,1994,66:38824MoussyF,HarrisonDJ,O’BrienDWetal.Performanceofsubcutaneouslyimplantedneedle-typeglucosesensorsemployinganoveltrilayercoating.Anal.Chem.,1993,65:20725CassAEG,DavisG,FrancisGDetal.Ferrocene-mediatedenzymeelectrodeforamperometricdeterminationofglucose.Anal.Chem.,1984,56:6676AtanasovP,KaisbevaA,GamburzevSetal.NickeIocene-mediatedglucoseoxidaseelectrode.Electroanalysis,1993,5:917GortonL,KaranHI,HalePDetal.Aglucoseelectrodebasedoncarbonpastechemicallymodifiedwithaferrocene-containingsiloxanepolymerandglucoseoxidase,coatedwithapoly(ester-sulfonicacid)cationexchanger.Anal.Chim.Acta,1990,228:238HalePD,LanHL,BoguslavskyLIetal.Amperometricglucosesensorsbasedonferrocene-modifiedpoly(ethyleneoxide)andglucoseoxidase.Anal.Chim,Acta,1991,251:1219OharaTJ,RaJagopalanR,HellerA.Glucoseelectrodesbasedoncross-linked[os(bpy)2Cl](+/2+)complexedpoly(1-vinylimidazole)films.Anal.Chem.,1993,65:351210YeL,HammerleM,OlsthoornAJJetal.Highcurrentdensity"wired"quinoproteingluasedehydrogenaseelectrode.AnalChem.,1993,65:23811ChaCS,LiCM,YangHXetal.Powdermicroelectrede.J.Electroanal.Chem.,1994,368:4712ChaCS,ChenJ,LiuPF.Improvementoftheoutputcharacteristicsofamperometricenzymeelectredebyusingpowdermicreelectrodetechnique.Submittdto"BivsensorandBivelectronics"13McCreeryRL.Carbonelectrodes:structuraleffectsonelectrontransferkinetics.Electroanal.Chem.,1991,17:221~37314DryhurstG.Electrochemistryoflowmolecularweightorgniccompandsofbiologicalinterest.ComprehensiveTreatiseofElectrochem.,Chap.2,1985,15:17415邓中一,王宗礼,李长明等。卟啉化合物的电催化行为(Ⅵ).高等学校化学学报,1987,8:45316ChaCS,ChenJ,LiuPF.ImprovementoftheadhesionofaNafionmodifyinglayeronelectrodes.J.Electroanal.Chem.,1993,345:46317荣国斌等。2-烷基环戊-2-烯酮的简便合成新法。化学学报,1983,41:971

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