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Corresponding Author

Gen_xi LI

Abstract

The research work of our group in the last two years is briefly reviewed in this paper. By using electrochemical method, and combining some other chemical and biological techniques, lots of achievements have been obtained. And these researches are towards some hot topics in life science, such as function conversion, interaction between signal molecules and proteins, electron_transfer of biomolecules, gene detection, structural biology, biochemical analysis and the third generation biosensors.

Keywords

Electrochemistry, Biochemistry, Biophysics, Biomedical engineering

Publication Date

2002-05-28

Online Available Date

2002-05-28

Revised Date

2002-05-28

Received Date

2002-05-28

References

[1] FanCH ,WangHY ,SunS ,etal.ElectrontransferreactivityandenzymaticactivityofhemoglobininaSPsephadexmembrane[J].Anal.Chem.,2001,73:2850.

[2] FanCH ,ZhuangY ,LiGX ,etal.Directelectrochemistryandenhancedcatalyticactivityforhemoglobininasodiummontmorillonitefilm[J].Electroanalysis,2000,33(14):1156.

[3] FanCH ,PangJT ,ShenPP ,etal.NitricoxidebiosensorsbasedonHb/phosphatidylcholinefilms[J].Ana lyticalScience,2002,18:129.

[4] FanCH ,ChenXC ,LiGX ,etal.Directelectrochemicalcharacterizationoftheinteractionbetweenhaemoglobinandnitricoxide[J].PCCP ,2000,2:4409.

[5] FanCH ,LiGX ,ZhuJQ ,etal.Areagentlessnitricoxidebiosensorbasedonhemoglobin_DNAfilms[J].AnalyticaChimicaActa,2000,423:95.

[6] FanCH ,WagnerG ,LiGX .Effectofdimethylsulfoxideontheelectrontransferreactivityofhemoglobin[J]Bioelectrochemistry,2001,54:49.

[7] FanCH ,LiGX ,GuQR ,etal.ElectrochemicaldetectionofcecropinCM 4 genebysinglestrandedprobeandcysteinemodifiedgoldelectrode[J].Anal.Lett.,2000,33(8):1479.

[8] FanCH ,HuXF ,LiGX ,etal.Adsorptivebehaviorofhemoglobinataplatinumelectrodeanditsapplicationtothedeterminationofproteins[J].Anal.Sci.,2000,16:463.

[9] FanCH ,SongHY ,HuXF ,etal.VoltammetricresponseanddeterminationofDNAatasilverelectrode[J].Anal.Biochem.,1999,271:1.

[10] FanCH ,SuzukiI ,ChenQ ,etal.Anunmediatedhydrogenperoxidesensorbasedonahemoglobin_SDSfilmmodifiedelectrode[J].Anal.Lett.,2000,33(13):2631.

[11] FanCH ,WangHY ,ZhuDX ,etal.Incorporationofhorseradishperoxidaseinakieselguhrmembraneandtheapplicationtoamediator_freehydrogenperoxidesensor[J].Anal.Sci.,2001,17:273.

[12] WangHY ,GuanR ,FanCH ,etal.Ahydrogenperoxidebiosensorbasedonthebioelectrocatalysisofhemoglobinincorporatedinakieselgubrfilm[J].SensorsandActuators,2002,84:204.

[13] FanCH ,GaoQX ,ZhuDX ,etal.Anunmediatedhydrogenperoxidebiosensorbasedonhemoglobinincor poratedinamontmorillonitemembrane[J].TheAnalyst,2001,126:1086.

[14] LiGX ,ChenL ,ZhuJQ ,etal.Histidinemodifiedelectrodeanditsapplicationtotheelectrochemicalstudiesofhemeproteins[J].Electroanalysis,1999,11(2):139.

[15] FanCH ,LiGX ,ZhuDX ,etal.Redoxreactionsofcytochromecfaciliatedbyimidazole_silvercomplex[J].ChineseJ.Chem.,2000,18(1):115.

[16] LiGX ,GuQR ,ZhuJQ ,etal.Preparationofpolyanilinemodifiedelectrodefortheelectroanalysisofhemeproteins[J].Anal.Lett.,1999,32(13):2545.

[17] FanCH ,LiGX ,ZhuangY ,etal.Iodidemodifiedsilverelectrodeanditsapplicationtotheelectroanalysisofhemoglobin[J].Electroanalysis,2000,12(3):205

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