Pre-oxidative Amperometric Glucose Biosensor Incorporated with Carbon Nanotube and PbO_(2)

Authors

Hong-lan QI, School of Chemistry and Materials Science,Shaanxi Normal University,Xi'an 710062,Shaanxi,China;
Cheng-xiao ZHANG, School of Chemistry and Materials Science,Shaanxi Normal University,Xi'an 710062,Shaanxi,China;

Corresponding Author

Cheng-xiao ZHANG(cxzhang@snnu.edu.cn)

Abstract

A pre-oxidative amperometric glucose biosensor incorporated with carbon nanotube,ferrocenemonocarboxylic acid and PbO_(2) was designed.The interferences coming from reduced substances,such as ascoribic acid and urine acid were eliminated by PbO_(2).The oxidative current is linear at the potential of +0.40 V(vs.SCE) to the concentration of glucose in the range from 0.50 to 20 mmol·L~(-1),and the detection limit of glucose is 0.1 mol L~(-1).The relative standard deviation is 3.3% for seven successive assays at 5.0 mmol·L~(-1)glucose.This biosensors have been applied to determination of the glucose in serum with satisfying results.

Keywords

Biosensor, Pre-oxidation, PbO_(2), Carbon nanotube, Glucose

DOI Link

https://doi.org/10.61558/2993-074X.1745

Publication Date

2006-08-28

Online Available Date

2006-08-28

Revised Date

2006-08-28

Received Date

2006-08-28

Recommended Citation

Hong-lan QI, Cheng-xiao ZHANG. Pre-oxidative Amperometric Glucose Biosensor Incorporated with Carbon Nanotube and PbO_(2)[J]. Journal of Electrochemistry, 2006 , 12(3): 319-323.
DOI: 10.61558/2993-074X.1745
Available at: https://jelectrochem.xmu.edu.cn/journal/vol12/iss3/17

References

[1]R icc i F,Pallesch i G.Sensor and b iosensor preparation,optim isation and app lications of Prussian B lue mod ifiedelectrodes[J].B iosensors and B ioelectron ics,2005,21:389.
[2]Xue H G,Shen Z Q,L i C M.Improved selectivity andstab ility of glucose b iosensor based on in situ electropoly-m erized polyan iline polyacrylon itrile composite film[J].B iosensors and B ioelectron ics,2005,20(11):2330.
[3]Zhang Z E,L iu H Y,Deng J Q.A glucose b iosensorbased on immob ilization of glucose oxidase in electropo-lym erizedo-am inophenol film on p latin ized glassy carbonelectrode[J].Anal.Chem.,1996,68(9):1632.
[4]Saby C,M izutan i F,Yabuk i S.G lucose sensor based oncarbon paste electrode incorporating poly(ethylene gly-col)-mod ified glucose oxidase and various m ed iators[J].Anal.Ch im.Acta,1995,304(1):33.
[5]Gh ica M E,B rett C M A.A glucose b iosensor usingm ethyl viologen redox m ed iator on carbon film electrodes[J].Anal.Ch im.Acta,2005,532(2):145.
[6]Poyard S,Jaffrezic-Renau lt N,M artelet C,et al.Opti-m ization of an inorgan ic/b io-organ ic m atrix for the devel-opm ent of new glucose b iosensor m embranes[J].Anal.Ch im.Acta,1998,364(1~3):165.
[7]Jung S K,W ilson G S.Polym eric m ercaptosilane-mod i-fied p latinum electrodes for elim ination of interferants inglucose b iosensors[J].Anal.Chem.,1996,68(4):591.
[8]Zhang S X,YangW W,N iu Y M,et al.Mu ltilayeredconstruction of glucose oxidase on gold electrodes basedon layer-by-layer covalent attachm ent[J].Anal.Ch im.Acta,2004,523(2):209.
[9]Cu i G,K im S J,Choi S H,et al.A d isposab le ampero-m etric sensor screen printed on a n itrocellu lose strip:Aglucose b iosensor emp loying lead oxide as an interference-removing agent[J].Anal.Chem.,2000,72(8):1925.
[10]Tang H,Chen J,Yao S,et al.Amperom etric glucoseb iosensor based on adsorption of glucose oxidase at p lati-num nanopartic le-mod ified carbon nanotube electrode[J].Anal.B iochem.,2004,331(1):89.
[11]Hrapovic S,L iu Y,M ale K B,et al.E lectrochem icalb iosensing p latform s using p latinum nanopartic les andcarbon nanotubes[J].Anal.Chem.,2004,76(4):1083.
[12]L im S H,W e i J,L in J,et al.A glucose b iosensorbased on electrodeposition of pallad ium nanopartic lesand glucose oxidase onto nafion-solub ilized carbonnanotube electrode[J].B iosens B ioelectron.,2005,20(11):2341.
[13]W u F H,Zhao G C,W e i X W.E lectrocatalytic oxida-tion of n itric oxide at mu lti-walled carbon nanotubesmod ified electrode[J].E lectrochem.Commun.,2002,4:690.
[14]Zhang C X,W ang K.An amperom etric glucose b iosen-sor incorporating a perm eab le pre-oxidation layer[J].Anal.Lett.,2002,35(5):869.
[15]Cass A E G,Davis G,Franc is G D,et al.Ferrocene-m ed iated enzym e electrode for amperom etric determ ina-tion of glucose[J].Anal.Chem.,1984,56(4):667.
[16]JIN L i-tong(金利通),MAO Y i-p ing(毛翼萍),FANG Yu-zh i(方禹之).Ferrocenemonocarboxylicac id-m ed iatored glucose b iosensor[J].Journal of EastCh ina Norm alUn iversity(Natural Sc ience),1995,2:59.