•  
  •  
 

Corresponding Author

Xin-hua LIN(xinhua63@163.com)

Abstract

The electrochemical behavior of TanshinoneⅡA was investigated by voltammetry at a glassy carbon electrode.And Differential Pulse Voltammetric method for determination of TanshinoneⅡA was developed.In pH 4.0 acetate buffer solution,the relationship between oxidation peak current of Differential Pulse Voltammetric and the concentration of Tanshinone ⅡA was linear in the range of 3.0×10 ~(-7)~2.0×10 ~(–5) mol·L~(-1).The detection limit had been estimated as 2.0×10~(-8) mol·L~(-1).The interference of other components in the preparation could be efficiently eliminated by the glassy carbon electrode.This method can be used for the determination of TanshinoneⅡA in real sample with satisfactory results

Keywords

TanshinoneⅡA, Glassy carbon electrode, Differential pulse voltammetric method

Publication Date

2006-11-28

Online Available Date

2006-11-28

Revised Date

2006-11-28

Received Date

2006-11-28

References

[1]ZHANG Yu-wu(张玉五),GAO Ya-fe i(高亚菲).Ad-vances of Salvia m iltiorrh iz,a drug for activating b loodc ircu lation to d issipate b lood stasis HDAC inh ib itor ap i-c id in and its antitumor[J].Journal of X i'an Jiaotong U-n iversity(M ed ical Sc iences)(in Ch inese),1990,11(3):191~195.
[2]ChangW L,Chen C F.Cytotoxic,activity of tansh inoneagains hum an carc inom acelllines[J].Am.J.Ch in.M ed.,1991,19(3):207~212.
[3]Y IN Hua(尹华),ZOU L i(邹莉),TANG L i-shan(谭丽姗).Determ ination ofTansh inoneⅡA in the gu jian oralliqu id by RP-HPLC[J].Ch inese Trad itional PatentM ed ic ine(in Ch inese),2005,11(27):10~12.
[4]PANG Zh i-gong(庞志功),WANG Bao-q i(汪宝琪),LIY ing-q ing(厉英倩).Determ ination of the b lood-drugconcentration of Tansh inoneⅡby m icelle fluorom etry[J].Journal of Analytical Sc ience,2000,16(6):488~491.
[5]Sh i Yan-p ing(师彦平),Yang X iao-pu(杨孝朴),L i Yu(李瑜).Stud ies on the chem ical constituents of SalviaPrzewalsk iiM axim and HPLC determ ination of Tansh i-none in ethanol extract[J].Journal of Lanzhou Un iver-istry(Natural Sc iences)(in Ch inese),1996,32(2):69~72.
[6]W u P ing(吴萍),Chen W e i(陈伟),Zhang Ya-feng(张亚锋),et al.E lectrochem ical behavior and determ ina-tion of curcum in[J].E lectrochem istry(in Ch inese),2005,11(3):346~349.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.