Corresponding Author

Chang-jian LIN(cjlin@xmu.edu.cn)


An electrochemical co-deposition technique has been developed to prepare a hydroxyapatite(HA)/collagen composite coating on Ti substrate.The SEM results show that the composite coating exhibits a homogeneous and porous morphology with nano-micro structure.And the XPS results demonstrate that the composite coating is formed by an organic-inorganic hybrization.In vitro cell culture tests reveal that,compared with pure HA and pure Ti,the HA/collagen composite coating exhibit a best biological properties.


hydroxyapatite, Ⅰtype collagen, composite coatings, electrochemical co-deposition, bioproperty

Publication Date


Online Available Date


Revised Date


Received Date



[1]Cheng Xiaoliang,Filiaggib Mark,Roscoe Sharon G.Electrochemically assisted co-precipitation of proteinwith calciumphosphate coatings on titaniumalloy[J].Biomaterials,2004,25:5395-5403.
[2]Fan Yuwei,Duan Ke,Wang Rizhi.A composite coatingby electrolysis-induced collagen self-assembly and calci-um phosphate mineralization[J].Biomaterials,2005,26:1623-1632.
[3]Wan Y Z,Hong L,Jia S R,et al.Synthesis andcharacterization of hydroyxyapatite-bacterial cellulosenanocomposites[J].Composites Science and Technolo-gy,2006,66:1825-1832.
[4]Hu Ren,Shi Haiyan,Lin Changjian.Anovel orderednano hydroxyapatite coating electrochemically depositedon titanium substrate[J].Journal of Biomedical Materi-als Research Part A,2007,80(3):687-692.
[5]Xu J L,Khor K A.Chemical analysis of silica dopedhydroxyapatite biomaterials consolidated by a sparkplasma sintering method[J].Journal of Inorganic Bio-chemistry,2007,101:187-195.
[6]Xue Weichang,Hosick Howard L,Bandyopadhyay Am-it,et al.Preparation and cell materials interactions ofplasma sprayed strontium-containing hydroxyapatitecoating[J].Surface&Coatings Technology,2007,201:4685-4693.



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.