Corresponding Author

Ren HU(renhu@xmu.edu.cn)


Charge transfer is one of the essential life processes. In the past decades, the electrochemical methods have been developed to study life science in a unique physicochemical view and have exhibited abundant and precious information beyond conventional biological techniques. As bioelectrochemical research areas evolved from the fundamental studies of biomolecules’ electrochemical behaviours in non-living conditions to the living cells in intro and in vivo, and further to the single molecule in living systems, the role of instruments becomes more and more crucial. The performances of instruments such as sensitivity, resolution (time, spatial and eneygy resolutions) and controllability are more demanding in the living conditions and at small size. In this review, the current statuses of the bioelectrochemical instruments, especially those for electrochemical studies at single living cell level, are presented; and the prospects of the domestic bioelectrochemical instruments are discussed.

Graphical Abstract


bioelectrochemical instruments, single living cell, review

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