Synergisms of Electric or Electromagnetic Fields and Photodynamic Effects Induce Apoptosis and Necrosis of Cancer Cells

Authors

Radeva Maria, Laboratory of Bioelectrochemistry, Campus Beutenberg, Jena, Germany
Lambrera Maya, Laboratory of Bioelectrochemistry, Campus Beutenberg, Jena, Germany
Angelova Plamena, Laboratory of Bioelectrochemistry, Campus Beutenberg, Jena, Germany
Traitcheva Nelly, Laboratory of Bioelectrochemistry, Campus Beutenberg, Jena, Germany
Berg Hermann, Laboratory of Bioelectrochemistry, Campus Beutenberg, Jena, GermanyFollow

Corresponding Author

Hermann Berg(hbergiena@hotmail.com)

Abstract

Weak pulsating sinusoidal electromagnetic fields (PEMF) have been applied to change membrane permeation and induction of apoptosis (necrosis). In the case of suspension of human cancer cells U-937 and K-562 inside of Helmholtz-coils the amplitude of PEMF B=10 and at 39mT (at 50 Hz) was combined gradually with the cytotoxic agent actinomycin-C on one hand with its novel photodynamic activity on the other.

Keywords

PEMF, Electroporation, Actinomycin-C, Photodynamics, Synergism, Cancer cells U-937, K-562

DOI Link

https://doi.org/10.61558/2993-074X.1573

Publication Date

2004-08-28

Online Available Date

2004-08-28

Revised Date

2004-05-23

Received Date

2003-04-19

Recommended Citation

Radeva Maria, Lambrera Maya, Angelova Plamena, Traitcheva Nelly, Berg Hermann. Synergisms of Electric or Electromagnetic Fields and Photodynamic Effects Induce Apoptosis and Necrosis of Cancer Cells[J]. Journal of Electrochemistry, 2004 , 10(3): 260-270.
DOI: 10.61558/2993-074X.1573
Available at: https://jelectrochem.xmu.edu.cn/journal/vol10/iss3/3