Oscillographic Determination of Ethamsylate

Authors

Hong-gang NI, Institute of Analytical Science, Shanxi Provincial Key Laboratory of Electroanalytical Chemistry, Northwest University, Xi'an 710069, China;
Hong-fang ZHANG, Institute of Analytical Science, Shanxi Provincial Key Laboratory of Electroanalytical Chemistry, Northwest University, Xi'an 710069, China;
Jian-bin ZHENG, Institute of Analytical Science, Shanxi Provincial Key Laboratory of Electroanalytical Chemistry, Northwest University, Xi'an 710069, China;

Corresponding Author

Jian-bin ZHENG

Abstract

In 0.2 mol L~(-1) NaOH solution, ethamsylate can yield a sensitive incision on cathodic branch of dE/dt-E osillogram at 0.3V (vs. SCE). Based on the oscillographic characteristic, a second order differential simple oscillographic voltammetry for determination of ethamsylate in tablet and injection is presented in this paper. The peak height on second order differential simple oscillographic voltammogram is linearly proportional to concentration of the ethamsylate in the range of 1.5×10~(-5)～3.4×10~(-4) mol·L~(-1 )with a 0.9921 correlation coefficient and a detection limit of 6.0×10~(-6 )mol·L~(-1 ) for ethamsylate. The relative standard deviation is 2.1% for the determination of 3.0 10~(-5) mol L~(-1) ethamsylate (n=5). Compared with HPLC and other methods, the second order differential simple oscillographic voltammetry is a convenient method due to its cheap equipment and rapid measurement.

Keywords

Oscillographic analysis, Oscillographic determination, Drug analysis, Ethamsylate

DOI Link

https://doi.org/10.61558/2993-074X.1645

Publication Date

2005-05-28

Online Available Date

2005-05-28

Revised Date

2005-05-28

Received Date

2005-05-28

Recommended Citation

Hong-gang NI, Hong-fang ZHANG, Jian-bin ZHENG. Oscillographic Determination of Ethamsylate[J]. Journal of Electrochemistry, 2005 , 11(2): 224-227.
DOI: 10.61558/2993-074X.1645
Available at: https://jelectrochem.xmu.edu.cn/journal/vol11/iss2/21

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