Electrochemical Impedance Spectrum of Ferrocene at a Rotating Disk Glassy Carbon Electrode and Its Interaction with DNA

Authors

Can-hui CHEN, 1),LI Hong ~(*1),~()ZHOU Jian-zhang~(2),LIN Zhong-hua~(2),ZHU Wei~(3),ZHANG Quan-xin~(3)(1.School of Chemistry and Environment,South China Normal University,Guangzhou 510006,Guangdong,China,2.State Key Laboratory for Physical Chemistry of the Solid Surface,Department of Chemistry,Institute of Physical Chemistry,Xiamen University,Xiamen 361005,Fujian,China,3.Unit of Molecular Toxicology,Center for Disease Control and Prevention,Guangzhou 510080,Guangdong,China;

Abstract

The electrochemical impedance spectrum(EIS) of ferrocene(Fc) at a rotating glassy carbon(GC) electrode and its interaction with calf thymus DNA in Tris-NaCl buffer solution(pH=7.2) have been investigated by using electrochemical techniques such as rotating disk electrode(RDE),EIS and its data fitting.A plateau of the limiting current for the voltammetric curve and two capacitance arches obtained at the rotating GC electrode are exhibited.The interaction of Fc with DNA is represented by the decrease of limiting diffusion current and the increase of electrochemical reaction resistances with the increase of DNA concentration,respectively.On the other hand,based on the theoretical analysis and data fitting of RDE and EIS,values of the rate constant at the formal potential obtained by RDE are consistent with those by EIS on the rotating GC electrode.At the same time,the rate constant at the formal potential decreases in the presence of DNA.

Keywords

Ferrocene, DNA, Rotating disk electrode, Electrochemical impedance spectrum

DOI Link

https://doi.org/10.61558/2993-074X.1717

Publication Date

2006-05-28

Online Available Date

2006-05-28

Revised Date

2006-05-28

Received Date

2006-05-28

Recommended Citation

Can-hui CHEN. Electrochemical Impedance Spectrum of Ferrocene at a Rotating Disk Glassy Carbon Electrode and Its Interaction with DNA[J]. Journal of Electrochemistry, 2006 , 12(2): 170-176.
DOI: 10.61558/2993-074X.1717
Available at: https://jelectrochem.xmu.edu.cn/journal/vol12/iss2/9