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Abstract

The electrochemical behavior of hemoglobin at glassy carbon(GC)electrode modified with Lauric Acid was studied.In the potential of +0.6~-0.7 V(vs.Ag/AgCl),an irreversible cathodic peak was observed at-0.3 V at the scan rate of 20 mV·s-1.In the medium of 0.02 mol·L-1 KH2PO4-Na2HPO4(pH 7.0),ip increased with the increasing concentration of Hb and the value of pH.The peak currents were proportional to the concentrations of hemoglobin in the range of 1.00×10-8~5.00×10-9 mol·L-1 and 1.92×10-6~2.06×10-7 mol·L-1.The data was analyzed in details by simulating in order to obtain more information and reaction mechanism of Hb on modified electrode.The electrode can be used as an approach for determining hemoglobin with high sensitivity.

Keywords

hemoglobin, cyclic voltammetry, modified electrode, lauric acid

Publication Date

2007-05-28

Online Available Date

2007-05-28

Revised Date

2007-05-28

Received Date

2007-05-28

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