Determination of Tetracyclines Based on the Flow-through Electrochemical Detection Cell with Nickel Electrode

Authors

Dan-mei PAN, Department of Chemistry and the MOE Key Laboratory of Analytical Sciences,Xiamen University,Xiamen 361005,Fujian,China,;
Rong-zong HU, Department of Chemistry and the MOE Key Laboratory of Analytical Sciences,Xiamen University,Xiamen 361005,Fujian,China,;
Dong-ping WEI, Department of Chemistry and the MOE Key Laboratory of Analytical Sciences,Xiamen University,Xiamen 361005,Fujian,China,;College of Chemistry and Ecological Engineering,Guangxi University for Nationalities,Nanning 530006,Guangxi,China;
Hao-dong DING, Department of Chemistry and the MOE Key Laboratory of Analytical Sciences,Xiamen University,Xiamen 361005,Fujian,China,;

Abstract

The electrochemical responses to tetracycline at the nickel electrode in alkaline solution were compared with that of gold and glassy carbon electrode by voltammetry.The electrocatalytic oxidation characteristics of tetracycline at nickel electrode were discussed.Subsequently a flow-through amperometric detection cell with nickel as the working electrode was designed to detect tetracycline,oxytetracycline,and doxycycline.Standard calibration graphs for the tetracyclines yielded linear ranges of 0.1~15 mg/L.Detection limits(S/N=3)of 35,45 and 43 μg/L were obtained for tetracycline,oxytetracycline and doxycycline,respectively.The system was applied for the determination of the three antibiotics in single-component drug formulations.

Keywords

nickel electrode, tetracyclines, electrocatalytic oxidation, flow-through cell

DOI Link

https://doi.org/10.61558/2993-074X.1792

Publication Date

2007-05-28

Online Available Date

2007-05-28

Revised Date

2007-05-28

Received Date

2007-05-28

Recommended Citation

Dan-mei PAN, Rong-zong HU, Dong-ping WEI, Hao-dong DING. Determination of Tetracyclines Based on the Flow-through Electrochemical Detection Cell with Nickel Electrode[J]. Journal of Electrochemistry, 2007 , 13(2): 122-126.
DOI: 10.61558/2993-074X.1792
Available at: https://jelectrochem.xmu.edu.cn/journal/vol13/iss2/2