Abstract
Voltammetric behavior of the Dopamine(DA) and ascorbic acid(AA) at Poly-Evans Blue modified electrode were studied and a novel method for determination of the content of DA and AA is established.In pH 4.5 phosphate buffer solution,the modified electrode shows enhanced sensitivity and excellent electrochemical discrimination to DA and AA.The relationship between oxidation peak current and the concentration of DA or AA is linear in the range of 1.0 10-6 ～3.0×10-5mol/L and 5.0×10-6~1.05×10-4 mol/L,the detection limit has been estimated as 2.5(10-7 mol/L and 3.0 ×10-7 mol/ L,respectively.The oxidable potential difference of DA and AA was about 184 mV at Poly-Evans Blue modified electrode.So it is used to simultaneously determine the DA and AA without any interference.The interference of other components could be efficiently eliminated at the modified electrode,and this method can be used for determination of DA and AA in real sample with satisfactory results.
Keywords
Evans blue, modified electrode, dopamine and ascorbic acid
Publication Date
2007-08-28
Online Available Date
2007-08-28
Revised Date
2007-08-28
Received Date
2007-08-28
Recommended Citation
Li-qing LIN, Xin-hua LIN, Hong YAO, Jing-hua CHEN, Guang-wen LI.
Electrocatalytic Separation for Dopamine and Ascorbic Acid Using Poly-Evans Blue Modified Glassy Carbon Electrode and Simultaneous Determination[J]. Journal of Electrochemistry,
2007
,
13(3): 329-333.
DOI: 10.61558/2993-074X.1832
Available at:
https://jelectrochem.xmu.edu.cn/journal/vol13/iss3/20
References
[1]Whitley R J,Meikle AW,Watts NB.Tietz textbook ofclinical chemistry[M].2nd Ed,Buurtis C A,AshwoodE R Edrs.Saunders:Philadelphia,1994.1793.
[2]WANG Huai-you(王怀友),SUN Yue(孙悦),TANGBo(唐波).Spectrophotometric determination of dopa-mine[J].Chin J Anal Lab,2003,22(01):45-47.
[3]WUXia(吴霞),TONG Shang-lun(童裳伦),SHUBen-yu(苏本玉),et al.Determination of dopamine by fluo-rimetry[J].Chin J Anal Chem,1999,27(9)1069-1071.
[4]YANG Na(杨娜),LI Jing(李静),ZHANG Lei(张雷).HPLC determination of dopamine hydrochloride indopamine hydrochloride and sodium chloride injection[J].Chin J Pharm Anal,2003,23(3):232-234.
[5]Zhang Y Z,Cai Y J,Su S.Determination of dopaminein the presence of ascorbic acid by poly(styrene sulfonicacid)sodium salt/single-wall carbon nanotube filmmodified glassy carbon electrode[J].Anal Biochem,2006,350(2):285-291.
[6]Vasantha V S,Chen S M.Electrocatalysis and simulta-neous detection of dopamine and ascorbic acid using po-ly(3,4-ethylenedioxy)thiophene film modified elec-trodes[J].2006,592(1):77-87.
[7]Wang Zhenhui(汪振辉),Jia Jianbo(郏建波),LiGongan(李工安),et al.Electrochemical behaviour ofdopamine on the polytheophylline/nafion dual-layermodified glassy carbon electrode[J].Chinese J AnalChem,2000,28(5):568-572.
[8]Bard A J,Faulkner L R.Electrochemical methods fun-damentals and applications[M].Beijing:Chemical In-dustry Press,2005.166.
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