Simultaneous Determination of Uric Acid(UA) and Ascorbic Acid(AA) at PCA/GC Electrode

Authors

REN Wang, College of Chemical & Pharmaceutical Engineering,Sichuan University of Science & Engineering,Zigong 643000,Sichuan,China;
Ying ZHANG, College of Chemical & Pharmaceutical Engineering,Sichuan University of Science & Engineering,Zigong 643000,Sichuan,China;
Jie DING, College of Chemical & Pharmaceutical Engineering,Sichuan University of Science & Engineering,Zigong 643000,Sichuan,China;

Abstract

Poly(cinnamic acid)-modified electrode (PCA /GC) was prepared by potentiostatic technique and was used for determination of uric acid (UA),ascorbic acid (AA),and their mixture by cyclic voltammetry. This modified electrode exhibited a potent and persistent electron-mediating behavior followed by well-separated oxidation peaks toward UA and AA at a scan rate of 50 mV·s-1 with a potential difference of 280 mV,which is large enough to determine UA and AA individually and simultaneously. The catalytic peak current obtained was linearly dependent on the UA and AA concentrations in the range of 2.0×10-6~1.0×10-4 mol·L-1,2.0×10-5~6.0×10-4 mol·L-1 in 0.03 mol·L-1 phosphate buffer (pH 6.0),respectively. The PCA /GC electrode showed good repeatability and could be used for determination of UA in urine samples.

Keywords

modified electrode, cinnamon acid, uric acid, ascorbic acid

DOI Link

https://doi.org/10.61558/2993-074X.2008

Publication Date

2009-08-28

Online Available Date

2009-08-28

Revised Date

2009-08-28

Received Date

2009-08-28

Recommended Citation

REN Wang, Ying ZHANG, Jie DING. Simultaneous Determination of Uric Acid(UA) and Ascorbic Acid(AA) at PCA/GC Electrode[J]. Journal of Electrochemistry, 2009 , 15(3): 345-349.
DOI: 10.61558/2993-074X.2008
Available at: https://jelectrochem.xmu.edu.cn/journal/vol15/iss3/22