Simultaneous Determinations of Ascorbic Acid, Dopamine and Uric Acid at CA/GC Electrode

Authors

Ying ZHANG, College of Chemical & Pharmaceutical Engineering, Sichuan University of Science & Engineering, Zigong, Sichuan 643000, China;
Wang REN, College of Chemical & Pharmaceutical Engineering, Sichuan University of Science & Engineering, Zigong, Sichuan 643000, China;
Min-Jiao LI, College of Chemical & Pharmaceutical Engineering, Sichuan University of Science & Engineering, Zigong, Sichuan 643000, China;

Corresponding Author

Ying ZHANG

Abstract

The citric acid modified glassy carbon electrode (CA/GC) was constructed by potentiostatic technique and used for simultaneous determinations of ascorbic acid (AA), dopamine (DA) and uric acid (UA) by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The CA/GC electrode exhibits excellent electrocatalytic activity towards AA, DA and UA. The oxidation peaks are well separated with the potential differences between AA and DA, DA and UA, and AA and UA being 170, 130 and 300 mV, respectively, which is large enough to determine AA, DA and UA simultaneously. The catalytic peak currents obtained were linearly dependent on the concentrations of AA, DA and UA in the range of 2.0×10-6~1.5×10-3 mol?L-1, 6.0×10-7~1.0×10-3 mol?L-1, and 6.0×10-7~1.0×10-3 mol?L-1, respectively. The proposed sensor shows good reproducibility and may be applied practically in the determinations of AA, DA and UA.

Graphical Abstract

Keywords

ascorbic acid, dopamine, uric acid, citric acid, modified electrode

DOI Link

https://doi.org/10.61558/2993-074X.2884

Publication Date

2012-02-28

Online Available Date

2011-09-29

Revised Date

2011-09-02

Received Date

2011-08-22

Recommended Citation

Ying ZHANG, Wang REN, Min-Jiao LI. Simultaneous Determinations of Ascorbic Acid, Dopamine and Uric Acid at CA/GC Electrode[J]. Journal of Electrochemistry, 2012 , 18(1): Article 13.
DOI: 10.61558/2993-074X.2884
Available at: https://jelectrochem.xmu.edu.cn/journal/vol18/iss1/13