Abstract
Protein post-translational modification is a key physiological procedure, which has received more and more research interests from the scientists not only in protein science but also in some other fields. The usually employed techniques for the study of protein modification include mass spectrum, affinity chromatography, etc. Considering the complexity of protein modification and the urgent demand of such kind of study, it is highly required to develop new techniques to perform more studies. Electrochemical methods, which have been widely used in chemical study and analysis, are playing an increasingly important role in many fields of biological studies. The modification of protein may induce chemical changes of specific groups, which may be characterized by using electrochemical methods via various approaches. Therefore, the changes of protein structure and function through protein modification can be revealed and the enzyme activity involved in protein modification may be detected rapidly, sensitively and accurately by taking the advantages of electrochemical methods, and consequently more and more achievements have been obtained. Based on some recent studies in the group of the authors and also some interesting works of other groups, this article reviews the progress of electrochemical study on protein modification, so as to exchange the research ideas with the colleagues in electrochemical community and some others related to protein science.
Graphical Abstract
Keywords
protein modification, protein electrochemistry, bioelectrochemistry, electrochemistry
Publication Date
2012-04-28
Online Available Date
2011-12-01
Revised Date
2011-11-21
Received Date
2011-10-11
Recommended Citation
Jing ZHAO, Xiao-Li ZHU, Gen-Xi LI.
Electrochemical Study of Protein Modification[J]. Journal of Electrochemistry,
2012
,
18(2): Article 1.
DOI: 10.61558/2993-074X.2887
Available at:
https://jelectrochem.xmu.edu.cn/journal/vol18/iss2/1
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