On the Molecular Mechanism of Electron Transfer of Cytochrome c Modulated by Gold Nanoparticles in Nano-Sandwich Architecture

Authors

Shou-Rui LIN, Department of Chemistry, Northeast Normal University, Changchun 130024, China
Li-Xu WANG, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun 130022, China；
Xiu-E JIANG, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun 130022, China；
Li-Ping GUO, Department of Chemistry, Northeast Normal University, Changchun 130024, China

Corresponding Author

Xiu-E JIANG(jiangxiue@ciac.ac.cn);Li-Ping GUO

Abstract

The effects of adsorbed gold nanoparticles on the surface-enhanced infrared absorption (SEIRA) difference spectra of redox-induced cytochrome (Cyt) c in AuNPs/Cyt c/Au sandwich architecture were monitored by SEIRA spectroscopy. The results indicated that the intensity of SEIRA difference spectrum for the vibration of the heme was significantly increased due to the adsorption of gold nanoparticles on the Cyt c. This was induced by the electron transfer between the heme and the gold nanoparticles, which also promoted electron transfer of adsorbed protein. This study suggested a new technique for optimizing the electrochemical property of adsorbed protein.

Graphical Abstract

Keywords

Cytochrome c, gold nanoparticles, surface-enhanced infrared absorption spectroscopy, electrochemistry

DOI Link

https://doi.org/10.61558/2993-074X.2913

Publication Date

2012-06-28

Online Available Date

2012-03-25

Revised Date

2012-03-21

Received Date

2011-11-29

Recommended Citation

Shou-Rui LIN, Li-Xu WANG, Xiu-E JIANG, Li-Ping GUO. On the Molecular Mechanism of Electron Transfer of Cytochrome c Modulated by Gold Nanoparticles in Nano-Sandwich Architecture[J]. Journal of Electrochemistry, 2012 , 18(3): Article 11.
DOI: 10.61558/2993-074X.2913
Available at: https://jelectrochem.xmu.edu.cn/journal/vol18/iss3/11