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Corresponding Author

Xin-hua LIN(xinhua63@163.com)

Abstract

The poly SudanⅢ modified electrode was characterized by electrochemical impedance spectroscopy(EIS)and cyclic voltammetry (CV), while the electrochemical behavior of paeonol was studied by cyclic voltammetry (CV). The result shows that the poly Sudan Ⅲ modified electrode exhibits excellent electrocatalytic effect on the oxidation of paeonol. The peak currents of differential pulse voltammetry are linear to the paeonol concentrations over the range of 3.0*10-7 ~ 2.2*10-5 mol·L-1. The detection limit has been estimated to be 5.0*10-8 mol·L-1. This method can be used for determination of paeonol content in real sample with satisfactory results.

Graphical Abstract

Keywords

Paeonol, Sudan Ⅲ, modified electrode, electrochemical behavior

Publication Date

2013-08-28

Online Available Date

2012-08-27

Revised Date

2012-08-23

Received Date

2012-07-11

References

[1] Yang Z S(杨正生), Peng Z H(彭振辉), Yao Q H (姚青海), et al. Progress on pharmacological research of paeonol[J]. Chinese Remedies & Clinics(中国药物与临床), 2011, 11(5): 545-546.

[2] Gao J H(高锦红), Zhang X Y(张学英), Zhu H Y(朱海燕). Determination of paeonol in radix cynanchi paniculati[J]. Chinese Journal of Spectroscopy Laboratory(光谱实验室), 2012, 29(2): 1207-1209.

[3] Li X Y(李向阳), Tu W Q(屠万倩). Determination of paeonol, paeoniflorin and ursolic acid in Liuwei Dihuang Pill by RP-HPLC[J]. Chinese Traditional Patent Medicine(中成药), 2012, 34(2): 277-282.

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[6] Wang Y, Wu J, Li D, et al. Electrochemical oxidation of paeonol and its reaction mechanism[J]. Chinese Journal of Analytical Chemistry, 2006, 34(9): 1331-1334.

[7] Zhang H J, Gao M M, Yang X F. Electrochemical oxidation and detection of paeonol on modified electrode with acetylene black nanoparticles[J]. Colloids and Surfaces B: Biointerfaces, 2011, 87(2): 378-381.

[8] Yang S L, Qu L B, Yang R, et al. Modified glassy carbon electrode with Nafion/MWNTs as a sensitive voltammetric sensor for the determination of paeonol in pharmaceutical and biological samples[J]. Journal of Applied Electrochemistry, 2010, 40(7): 1371-1378.

[9] Chinese pharmacopoeia commission. Pharmacopoeia of People's Republic of China (?)[M]. Beijing: China Medical Science and Technology Press, 2010: 161.

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