Electrochemiluminescence Assay Based on Bipolar Electrode for Bioanalysis

Authors

Mei-sheng WU, State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China;Department of Chemistry, College of Science, Nanjing Agricultural University, Nanjing 210095, China;
Jing-juan XU, State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China;Follow
Hong-yuan CHEN, State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China;

Corresponding Author

Jing-juan XU(xujj@nju.edu.cn)

Abstract

Bipolar electrodes (BPEs) are electronic conductors which are usually embedded into microchannels. The potential difference at the BPE/solution interface is obtained by applying a voltage at the two ends of the microchannel. When it reaches a critical value, the redox reaction takes place at both poles of the BPE simultaneously. Compared with other detection methods, the electrochemiluminescence (ECL) platform based on BPE possesses the advantages of concentration enrichment, high sensitivity, low cost, portable sensor system, no need for a light source, which is quite suitable for bioanalysis. This paper reviews the ECL-BPE strategy for bioanalysis and proposes the future research trends.

Graphical Abstract

Keywords

bipolar electrode, electrochemiluminescence, Ru(bpy)32+, biosensor array

DOI Link

https://doi.org/10.13208/j.electrochem.140444

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Publication Date

2015-02-28

Online Available Date

2014-12-07

Revised Date

2014-12-01

Received Date

2014-11-12

Recommended Citation

Mei-sheng WU, Jing-juan XU, Hong-yuan CHEN. Electrochemiluminescence Assay Based on Bipolar Electrode for Bioanalysis[J]. Journal of Electrochemistry, 2015 , 21(1): 1-7.
DOI: 10.13208/j.electrochem.140444
Available at: https://jelectrochem.xmu.edu.cn/journal/vol21/iss1/1