Fabrication of Riboflavin Electrochemical Sensor Based on Au Nanoparticles/Polydopamine/Carbon Nanotubes Modified Glassy Carbon Electrode

Authors

Hua-ping PENG, The higher educational key laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical Univeristy，Fuzhou 350004，China
Mei-ling YU, Department of Pharmaceutical Analysis of the Fujian Medical University，Fuzhou 350004，China；
Xin LIU, Department of Pharmaceutical Analysis of the Fujian Medical University，Fuzhou 350004，China；
Pan LIU, The higher educational key laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical Univeristy，Fuzhou 350004，China
Wei CHEN, The higher educational key laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical Univeristy，Fuzhou 350004，China
Ai-lin LIU, The higher educational key laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical Univeristy，Fuzhou 350004，China
Xin-hua LIN, The higher educational key laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical Univeristy，Fuzhou 350004，China

Corresponding Author

Xin-hua LIN(xinhua63@163.com)

Abstract

A novel electrochemical platform for the high sensitivity detection of riboflavin was constructed by Au nanoparticles/polydopamine/carbon nanotubes (Au-PDA-MWCNTs) nanocomposite modified glassy carbon electrode. The Au-PDA-MWCNTs nanocomposite was synthesized by in situ reduction method. The characteristics of the as-prepared Au-PDA-MWCNTs nanocomposite modified electrodes were investigated by using UV-Vis spectroscopy, scanning electron microscopy (SEM) and electrochemical methods. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used to study the electrochemical behavior of riboflavin (RF) at Au-PDA-MWCNTs nanocomposite modified electrodes. The results demonstrated that the present electrochemical sensor exhibited a wide linear range from 5×10^-9 mol•L^-1to 1×10^-5 mol•L^-1 for detection of riboflavin, with a detection limit of 1.7×10^-9 mol•L^-1 (S/N = 3). The present method for high sensitivity determination of riboflavin by electrochemical method at Au-PDA-MWCNTs nanocomposite modified electrodes is simple, accurate, reliable and feasible with an excellent anti-interference ability against electroactive species and metal ions. Accordingly, the present method proved to be useful for the estimation of the RF content in pharmaceutical samples with satisfactory recovery.

Graphical Abstract

Keywords

riboflavin, gold nanoparticles, polydopamine, multi-walled carbon nanotubes, electrochemistry

DOI Link

https://doi.org/10.13208/j.electrochem.150727

Publication Date

2016-02-29

Online Available Date

2015-09-06

Revised Date

2015-09-03

Received Date

2015-07-27

Recommended Citation

Hua-ping PENG, Mei-ling YU, Xin LIU, Pan LIU, Wei CHEN, Ai-lin LIU, Xin-hua LIN. Fabrication of Riboflavin Electrochemical Sensor Based on Au Nanoparticles/Polydopamine/Carbon Nanotubes Modified Glassy Carbon Electrode[J]. Journal of Electrochemistry, 2016 , 22(1): 150727.
DOI: 10.13208/j.electrochem.150727
Available at: https://jelectrochem.xmu.edu.cn/journal/vol22/iss1/13