Electrochemical Behaviors and Determinations of Terbutaline Sulfate at Poly Eriochrome Black T Modified Electrode

Authors

Yan-jie ZHENG, Department of Pharmaceutical Analysis of Fujian Medical University，Fuzhou 350108，China;The Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University，Fuzhou 350108，China;
Hong YAO, Department of Pharmaceutical Analysis of Fujian Medical University，Fuzhou 350108，China;The Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University，Fuzhou 350108，China;
Shao-huang WENG, Department of Pharmaceutical Analysis of Fujian Medical University，Fuzhou 350108，China;The Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University，Fuzhou 350108，China;
Hua-ping PENG, Department of Pharmaceutical Analysis of Fujian Medical University，Fuzhou 350108，China;The Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University，Fuzhou 350108，China;
Shi-wen GONG, Department of Pharmaceutical Analysis of Fujian Medical University，Fuzhou 350108，China;
Li HUANG, Department of Pharmaceutical Analysis of Fujian Medical University，Fuzhou 350108，China;
Qiang DAI, Department of Pharmaceutical Analysis of Fujian Medical University，Fuzhou 350108，China;
Xin-hua LIN, Department of Pharmaceutical Analysis of Fujian Medical University，Fuzhou 350108，China;The Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University，Fuzhou 350108，China;Follow

Corresponding Author

Xin-hua LIN(xinhua63@163.com)

Abstract

The poly eriochrome black T modified electrode was prepared by electropolymerization. This modified electrode was characterized by scanning electron microscopy(SEM), electrochemical impedance spectroscopy(EIS) and cyclic voltammetry (CV). The electrochemical behaviors of terbutaline sulfate were studied by CV, while the recoveries were measured by differential pulse voltammetry (DPV). The modified electrode shows excellent electrocatalytic characteristics for terbutaline sulfate. In pH 7.0 phosphate buffer solution, the oxidation peak currents obtained by DPV were linear to the terbutaline sulfate concentrations over the range of 1.2x10^-7~2.0x10^-6 mol•L^-1. The detection limit was estimated to be 1.5x10^-8 mol•L^-1 and the average recovery was 97.9%～104.6%. The relative standard deviation (RSD) was 2.8% for 8x10^-7mol•L^-1terbutaline sulfate (n=11). This method is simple, sensitive, and accurate with good repeatability, and can be used for the determination of terbutaline sulfate and the corresponding tablets.

Graphical Abstract

Keywords

terbutaline sulfate, poly eriochrome black T modified electrode, cyclic voltammetry, differential pulse voltammetry

DOI Link

https://doi.org/10.13208/j.electrochem.160107

Publication Date

2016-12-28

Online Available Date

2016-02-19

Revised Date

2016-02-14

Received Date

2016-01-07

Recommended Citation

Yan-jie ZHENG, Hong YAO, Shao-huang WENG, Hua-ping PENG, Shi-wen GONG, Li HUANG, Qiang DAI, Xin-hua LIN. Electrochemical Behaviors and Determinations of Terbutaline Sulfate at Poly Eriochrome Black T Modified Electrode[J]. Journal of Electrochemistry, 2016 , 22(6): 617-623.
DOI: 10.13208/j.electrochem.160107
Available at: https://jelectrochem.xmu.edu.cn/journal/vol22/iss6/10