Application of Nanomaterials in the Detection of Volatile Organic Compounds in Exhaled Breath for Cancer Diagnosis

Authors

Wan-qiao BAI, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, The Chinese Academy of Sciences, Beijing 100190, China;
Xue-zhi QIAO, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, The Chinese Academy of Sciences, Beijing 100190, China;
Tie WANG, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, The Chinese Academy of Sciences, Beijing 100190, China;University of Chinese Academy of Sciences, Beijing 100049, China;Follow

Corresponding Author

Tie WANG(wangtie@iccas.ac.cn)

Abstract

Volatile organic compounds (VOCs) generated in human body can reflect one’s health state, and numerous diseases are identified by some VOCs biomarkers. More recently, analyses of VOCs biomarkers from exhaled breath have turned into a research frontier worldwide because it offers a noninvasive way for diseases diagnosis. Various kinds of nanomaterials are used to enhance the performance of sensing techniques, and play an essential role in miniaturization detection. In this review, several kinds of nanomaterials (metallic, metal oxide, carbon-based, composites and MOFs-based materials) used in various VOCs detection methods, especially in VOCs sensors are summarized. Learning from the successful utilization of nanomaterials in these methods will help to further understand the superiority and limitation of detection techniques. A personal perspective of the research and development in exhaled breath VOCs detection for cancer diagnosis has been presented.

Graphical Abstract

Keywords

volatile organic compounds, nanomaterials, cancer, biomarker, exhaled breath

DOI Link

https://doi.org/10.13208/j.electrochem.181041

Publication Date

2019-04-28

Online Available Date

2018-11-22

Revised Date

2018-11-06

Received Date

2018-10-09

Recommended Citation

Wan-qiao BAI, Xue-zhi QIAO, Tie WANG. Application of Nanomaterials in the Detection of Volatile Organic Compounds in Exhaled Breath for Cancer Diagnosis[J]. Journal of Electrochemistry, 2019 , 25(2): 185-201.
DOI: 10.13208/j.electrochem.181041
Available at: https://jelectrochem.xmu.edu.cn/journal/vol25/iss2/5