Quantitative Detection of Levofloxacin Hydrochloride by Differential Pulse Stripping Voltammetry with Electrodeposited Bismuth Film Electrodes

Authors

Zi-ying GUO, School of Chemistry and Enviromental Engineering, Shanxi Datong University, Datong, 037009, China;
Zuo-peng LI, School of Chemistry and Enviromental Engineering, Shanxi Datong University, Datong, 037009, China;
Jiang LI, School of Chemistry and Enviromental Engineering, Shanxi Datong University, Datong, 037009, China;
Jian-guo ZHAO, School of Chemistry and Enviromental Engineering, Shanxi Datong University, Datong, 037009, China;
Feng FENG, School of Chemistry and Enviromental Engineering, Shanxi Datong University, Datong, 037009, China;

Corresponding Author

Zuo-peng LI(lizuopeng@126.com);
Feng FENG(feng-feng64@263.net)

Abstract

In this study, differential pulse stripping voltammetry was developed for the quantitative detection of levofloxacin hydrochloride indirectly. Levofloxacin hydrochloride contains organic amine, which can be precipitated upon interaction with Zn(SCN)₄^2-. By means of differential pulse stripping voltammetry, the concentration of Zn²⁺ can be determined using an in-situ formed bismuth film electrode, which allows determining indirectly the amount of levofloxacine hydrochloride. The linearity equation, I = 1.1401c - 0.5309 with the correlative coefficient R = 0.9979, was presented in the experiment. The results showed that this approach is very sensitive, having a limitation of detection of 3.18 × 10^-5 μg·mL^-1 in a linearity range of 5.0 ~ 60 μg·mL^-1.

Graphical Abstract

Keywords

bismuth film electrode, differential pulse stripping voltammetry, levofloxacine hydrochloride, zinc ion, ion-association compound

DOI Link

https://doi.org/10.13208/j.electrochem.180924

Publication Date

2019-12-28

Online Available Date

2018-12-26

Revised Date

2018-12-04

Received Date

2018-09-26

Recommended Citation

Zi-ying GUO, Zuo-peng LI, Jiang LI, Jian-guo ZHAO, Feng FENG. Quantitative Detection of Levofloxacin Hydrochloride by Differential Pulse Stripping Voltammetry with Electrodeposited Bismuth Film Electrodes[J]. Journal of Electrochemistry, 2019 , 25(6): 792-801.
DOI: 10.13208/j.electrochem.180924
Available at: https://jelectrochem.xmu.edu.cn/journal/vol25/iss6/17